Product Development

Commonhealth. Page 10. 1958

Timeline

  • 1894
    Massachusetts Board of Health established Antitoxin and Vaccine Laboratory.
  • 1904
    Production and distribution begun on Smallpox vaccine.
  • 1910
    Production and distribution begun on Silver nitrate solution, used to prevent newborn blindness from neonatal inflammatory eye disease.
  • 1912
    Production and distribution begun on typhoid vaccine.
  • 1913
    Production and distribution begun on antimenigitis serum, lasting until 1945.
  • 1914
    Diphtheria vaccine introduced into general use in Massachusetts.
  • 1915
    The use and production of the Schick test for diphtheria immunity begun.
  • 1917
    Granted Federal License #64 authorizing manufacture and interstate sale of biologic products.
  • 1917
    Production and distribution begun on anti-pneumococcus serum.
  • 1918
    Production and distribution begun on Diphtheria Toxin-Antitoxin, lasting until 1947.
  • 1925
    Production and distribution begun on scarlet fever antitoxin, lasting until 1949.
  • 1927
    Production and distribution begun on Influenza Bacillus Antiserum, lasting until 1950.
  • 1930
    Production and distribution begun on Tuberculin.
  • 1930
    Production and distribution begun on Pneumococcus Diagnostic Serum, lasting until 1947.
  • 1933
    Production and distribution begun on Poliomyelitis and Scarlet Fever Convalescent Serums, both lasting until 1938. As well, Scarlet Fever Steptococcus Toxoid (until 1948) and Toxin (until 1950).
  • 1934
    Distribution begun of Placental extract, lasting until 1945.
  • 1941
    Production and distribution begun on tetanus vaccine.
  • 1941
    Distribution of Normal Serum Albumin (human) begun.
  • 1942
    Distribution of Immune Serum Globulin manufactured by the Cohn cold-ethanol process begun.
  • 1946
    Production and distribution begun on Citrated Whole Blood, lasting until 1950.
Product Display

Display of Blood Products. 1940s.

  • 1949
    Production and distribution begun on pertussis vaccine, Tetanus toxoid, and a purified Diphtheria Toxoid.
  • 1950
    Production and distribution begun onĀ  “combination vaccine”, a Diphtheria-Tetanus-Pertussis vaccine.
  • 1962
    Production and distribution begun on Tetanus Immune Globulin.
  • 1970
    Production and distribution begun on Rh Immune Globulin for prevention of Rh hemolytic disease of the newborn.
  • 1972
    Production and distribution begun on Hepatitis B Immune Globulin.
  • 1981
    Production and distribution begun on Varicella Zoster Immune Globulin.
  • 1990
    Production and distribution begun on Cytomegalovirus Immune Globulin.
  • 1996
    Production and distribution begun on Respiratory Syncytial Virus Immune Globulin.

Smallpox Vaccine Tuck - Package design and order approval by James McComb. 1953Smallpox Vaccine Tuck - Package design and order approval by George Grady. November 30, 1973
Smallpox vaccine tucks [individual product boxes]- package order and approval, 1953 and 1973

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