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(MedPage Today) -- A set of simple interventions developed by the CDC can markedly reduce bloodstream infections among hemodialysis patients, researchers reported.

Melting ice in Greenland may have helped to shift the location of the North Pole.

Nature News doi: 10.1038/nature.2013.12994

DNA casts doubt on Egyptian origin for ancient Cretans.

Nature News doi: 10.1038/nature.2013.12990

Initiative will use crowdsourced data to inform global carbon modelling.

Nature News doi: 10.1038/nature.2013.12969

Controlled explosions could aid monitoring of active eruptions.

Nature News doi: 10.1038/nature.2013.12970

(MedPage Today) -- SILVER SPRING, Md. -- The FDA has approved radium-223 dichloride (Xofigo) for treating bone metastases from castration-resistant prostate cancer, the agency said Wednesday.

(MedPage Today) -- SILVER SPRING, Md. -- The FDA has approved radium-223 dichloride (Xofigo) for treating bone metastases from castration-resistant prostate cancer, the agency said Wednesday.

Throughout the animal kingdom, steroid hormones have been implicated in the defense against microbial infection, but how these systemic signals control immunity is unclear. Here, we show that the steroid hormone ecdysone controls the expression of the pattern recognition receptor PGRP-LC in Drosophila, thereby tightly regulating innate immune recognition and defense against bacterial infection. We identify a group of steroid-regulated transcription factors as well as two GATA transcription factors that act as repressors and activators of the immune response and are required for the proper hormonal control of PGRP-LC expression. Together, our results demonstrate that Drosophila use complex mechanisms to modulate innate immune responses, and identify a transcriptional hierarchy that integrates steroid signalling and immunity in animals.

(MedPage Today) -- Women who have a hysterectomy with or without removal of the ovaries in mid-life do not appear to have an increased risk of cardiovascular disease, researchers found.

(MedPage Today) -- Women who have a hysterectomy with or without removal of the ovaries in mid-life do not appear to have an increased risk of cardiovascular disease, researchers found.

(MedPage Today) -- Opioid use, particularly long-term use, may be associated with erectile dysfunction and low testosterone, researchers found.

(MedPage Today) -- Opioid use, particularly long-term use, may be associated with erectile dysfunction and low testosterone, researchers found.

Bacterium helps to regulate metabolism in mice.

Nature News doi: 10.1038/nature.2013.12975

Comparison between hominins suggests modern middle-ear bones evolved early.

Nature News doi: 10.1038/nature.2013.12976

Funding goal for 2020 revised from 3% of GDP to 2%, and state share will be cut.

Nature News doi: 10.1038/nature.2013.12964

(MedPage Today) -- Dual-chamber implantable cardioverter-defibrillators (ICDs) dominate, perhaps undeservedly, among primary prevention patients without a clear need for pacing, a U.S. national registry study suggested.

Protein relieves age-related stiffening and thickening of cardiac muscle.

Nature News doi: 10.1038/nature.2013.12971

(MedPage Today) -- When Angelina Jolie charted her course of action against the breast cancer cards she'd been dealt, she didn't seek direction from an academic medical center.

Critics say clinical manual unfit for mental-health research.

Nature News doi: 10.1038/nature.2013.12972

WASHINGTON (MedPage Today) -- The FDA has approved a companion EGFR mutation test for use with the targeted cancer drug erlotinib (Tarceva) to help guide decision making in non-small cell lung cancer.